Quantifying 3D Traction Forces of Epithelial Cell Clusters @ California Institute of Technology

Highlight

Author(s):

Anand Asthagiri and Guruswami Ravichandran

When cells assemble together in a cluster, they apply force to each other. The way in which cells signal each other with and respond to forces is not well understood. Therefore, we study the traction forces cells apply to the substrate beneath them. The results show exterior cells apply tractions to the substrate that are an order of magnitude larger than the tractions the interior cells apply.

Attachment
CalTech MRSEC 0520565 Quantifying 3D Traction Forces of Epithelial Cell Clusters.pdf