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Recent Program Highlights

Field-effect transistor (FET)-based biosensors allow label-free detection of biomolecules by measuring their intrinsic charges. We previously reported the extremely low limit of detection on electrical field effect-based sensors using crumpled graphene. Here, we use FETs with a deformed monolayer graphene channel for the detection of various biomarkers.

A disordered material’s structure and macroscopic mechanical response are related in a non-trivial way. By studying a 2D jammed colloidal system under oscillatory shear, our study elucidates this link in the transition from elasticity to plasticity based on microstructural signatures.

We developed one-component, sequence-defined Ionizable Amphiphilic Janus Dendrimers (IAJDs) and their assemblies with mRNA. These Dendrimersome Nanoparticles (DNPs) were investigated for the delivery of mRNA for vaccines and nanotherapeutics.

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